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The Non-Coding Oncogene: A Case of Missing DNA Evidence?

The evidence that links classical protein-coding proto-oncogenes and tumor suppressors, such as MYC, RAS, P53, and RB, to carcinogenesis is indisputable. Multiple lines of proof show how random somatic genomic alteration of such genes (e.g., mutation, deletion, or amplification), followed by selecti...

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Detalles Bibliográficos
Autores principales: Shahrouki, Puja, Larsson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439828/
https://www.ncbi.nlm.nih.gov/pubmed/22988449
http://dx.doi.org/10.3389/fgene.2012.00170

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