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Towards characterization of DNA structure under physiological conditions in vivo at the single-molecule level using single-pair FRET
Fluorescence resonance energy transfer (FRET) under in vivo conditions is a well-established technique for the evaluation of populations of protein bound/unbound nucleic acid (NA) molecules or NA hybridization kinetics. However, in vivo FRET has not been applied to in vivo quantitative conformationa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439876/ https://www.ncbi.nlm.nih.gov/pubmed/22544706 http://dx.doi.org/10.1093/nar/gks333 |