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Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds
A new strategy to create site-specific, homogeneous, and bright silver nanoclusters (AgNCs) with high-stability was demonstrated by triplex DNA as template. By reasonable design of DNA sequence, homogeneous Ag(2) cluster was obtained in the predefined position of CG.C(+) site of triplex DNA. This st...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439878/ https://www.ncbi.nlm.nih.gov/pubmed/22570417 http://dx.doi.org/10.1093/nar/gks387 |
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author | Feng, Lingyan Huang, Zhenzhen Ren, Jinsong Qu, Xiaogang |
author_facet | Feng, Lingyan Huang, Zhenzhen Ren, Jinsong Qu, Xiaogang |
author_sort | Feng, Lingyan |
collection | PubMed |
description | A new strategy to create site-specific, homogeneous, and bright silver nanoclusters (AgNCs) with high-stability was demonstrated by triplex DNA as template. By reasonable design of DNA sequence, homogeneous Ag(2) cluster was obtained in the predefined position of CG.C(+) site of triplex DNA. This strategy was also explored for controlled alignment of AgNCs on the DNA nanoscaffold. To the best of our knowledge, this was the first example to simultaneously answer the challenges of excellent site-specific nucleation and growth, homogeneity and stability against salt of DNA-templated AgNCs. |
format | Online Article Text |
id | pubmed-3439878 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-34398782012-09-12 Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds Feng, Lingyan Huang, Zhenzhen Ren, Jinsong Qu, Xiaogang Nucleic Acids Res Methods Online A new strategy to create site-specific, homogeneous, and bright silver nanoclusters (AgNCs) with high-stability was demonstrated by triplex DNA as template. By reasonable design of DNA sequence, homogeneous Ag(2) cluster was obtained in the predefined position of CG.C(+) site of triplex DNA. This strategy was also explored for controlled alignment of AgNCs on the DNA nanoscaffold. To the best of our knowledge, this was the first example to simultaneously answer the challenges of excellent site-specific nucleation and growth, homogeneity and stability against salt of DNA-templated AgNCs. Oxford University Press 2012-09 2012-05-08 /pmc/articles/PMC3439878/ /pubmed/22570417 http://dx.doi.org/10.1093/nar/gks387 Text en © The Author(s) 2012. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Methods Online Feng, Lingyan Huang, Zhenzhen Ren, Jinsong Qu, Xiaogang Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds |
title | Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds |
title_full | Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds |
title_fullStr | Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds |
title_full_unstemmed | Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds |
title_short | Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds |
title_sort | toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex dna scaffolds |
topic | Methods Online |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439878/ https://www.ncbi.nlm.nih.gov/pubmed/22570417 http://dx.doi.org/10.1093/nar/gks387 |
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