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Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds

A new strategy to create site-specific, homogeneous, and bright silver nanoclusters (AgNCs) with high-stability was demonstrated by triplex DNA as template. By reasonable design of DNA sequence, homogeneous Ag(2) cluster was obtained in the predefined position of CG.C(+) site of triplex DNA. This st...

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Detalles Bibliográficos
Autores principales: Feng, Lingyan, Huang, Zhenzhen, Ren, Jinsong, Qu, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439878/
https://www.ncbi.nlm.nih.gov/pubmed/22570417
http://dx.doi.org/10.1093/nar/gks387
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author Feng, Lingyan
Huang, Zhenzhen
Ren, Jinsong
Qu, Xiaogang
author_facet Feng, Lingyan
Huang, Zhenzhen
Ren, Jinsong
Qu, Xiaogang
author_sort Feng, Lingyan
collection PubMed
description A new strategy to create site-specific, homogeneous, and bright silver nanoclusters (AgNCs) with high-stability was demonstrated by triplex DNA as template. By reasonable design of DNA sequence, homogeneous Ag(2) cluster was obtained in the predefined position of CG.C(+) site of triplex DNA. This strategy was also explored for controlled alignment of AgNCs on the DNA nanoscaffold. To the best of our knowledge, this was the first example to simultaneously answer the challenges of excellent site-specific nucleation and growth, homogeneity and stability against salt of DNA-templated AgNCs.
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spelling pubmed-34398782012-09-12 Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds Feng, Lingyan Huang, Zhenzhen Ren, Jinsong Qu, Xiaogang Nucleic Acids Res Methods Online A new strategy to create site-specific, homogeneous, and bright silver nanoclusters (AgNCs) with high-stability was demonstrated by triplex DNA as template. By reasonable design of DNA sequence, homogeneous Ag(2) cluster was obtained in the predefined position of CG.C(+) site of triplex DNA. This strategy was also explored for controlled alignment of AgNCs on the DNA nanoscaffold. To the best of our knowledge, this was the first example to simultaneously answer the challenges of excellent site-specific nucleation and growth, homogeneity and stability against salt of DNA-templated AgNCs. Oxford University Press 2012-09 2012-05-08 /pmc/articles/PMC3439878/ /pubmed/22570417 http://dx.doi.org/10.1093/nar/gks387 Text en © The Author(s) 2012. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Methods Online
Feng, Lingyan
Huang, Zhenzhen
Ren, Jinsong
Qu, Xiaogang
Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds
title Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds
title_full Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds
title_fullStr Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds
title_full_unstemmed Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds
title_short Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds
title_sort toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex dna scaffolds
topic Methods Online
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439878/
https://www.ncbi.nlm.nih.gov/pubmed/22570417
http://dx.doi.org/10.1093/nar/gks387
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