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Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation

The Srs2 DNA helicase of Saccharomyces cerevisiae affects recombination in multiple ways. Srs2 not only inhibits recombination at stalled replication forks but also promotes the synthesis-dependent strand annealing (SDSA) pathway of recombination. Both functions of Srs2 are regulated by sumoylation—...

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Detalles Bibliográficos
Autores principales: Kolesar, Peter, Sarangi, Prabha, Altmannova, Veronika, Zhao, Xiaolan, Krejci, Lumir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439891/
https://www.ncbi.nlm.nih.gov/pubmed/22705796
http://dx.doi.org/10.1093/nar/gks484

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