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Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress
Upon DNA damage induction, DNA-dependent poly(ADP-ribose) polymerases (PARPs) synthesize an anionic poly(ADP-ribose) (pADPr) scaffold to which several proteins bind with the subsequent formation of pADPr-associated multiprotein complexes. We have used a combination of affinity-purification methods a...
Autores principales: | Gagné, Jean-Philippe, Pic, Émilie, Isabelle, Maxim, Krietsch, Jana, Éthier, Chantal, Paquet, Éric, Kelly, Isabelle, Boutin, Michel, Moon, Kyung-Mee, Foster, Leonard J., Poirier, Guy G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439892/ https://www.ncbi.nlm.nih.gov/pubmed/22669911 http://dx.doi.org/10.1093/nar/gks486 |
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