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Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus

An adaptive response to alkylating agents based upon the conformational change of a methylphosphotriester (MPT) DNA repair protein to a transcriptional activator has been demonstrated in a number of bacterial species, but this mechanism appears largely absent from eukaryotes. Here, we demonstrate th...

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Detalles Bibliográficos
Autores principales: O’Hanlon, Karen A., Margison, Geoffrey P., Hatch, Amy, Fitzpatrick, David A., Owens, Rebecca A., Doyle, Sean, Jones, Gary W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439912/
https://www.ncbi.nlm.nih.gov/pubmed/22669901
http://dx.doi.org/10.1093/nar/gks522