Cargando…

Translation initiation without IF2-dependent GTP hydrolysis

Translation initiation factor IF2 is a guanine nucleotide-binding protein. The free energy change associated with guanosine triphosphate hydrolase (GTPase) activity of these proteins is believed to be the driving force allowing them to perform their functions as molecular switches. We examined role...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fabbretti, Attilio, Brandi, Letizia, Milón, Pohl, Spurio, Roberto, Pon, Cynthia L., Gualerzi, Claudio O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439930/ https://www.ncbi.nlm.nih.gov/pubmed/22723375 http://dx.doi.org/10.1093/nar/gks569

Ejemplares similares

The antibiotic Furvina® targets the P-site of 30S ribosomal subunits and inhibits translation initiation displaying start codon bias
por: Fabbretti, Attilio, et al.
Publicado: (2012)

The dynamic cycle of bacterial translation initiation factor IF3
por: Nakamoto, Jose A, et al.
Publicado: (2021)

Ribosomal selection of mRNAs with degenerate initiation triplets
por: Chengguang, He, et al.
Publicado: (2017)

Translation initiation factor IF2 contributes to ribosome assembly and maturation during cold adaptation
por: Brandi, Anna, et al.
Publicado: (2019)

Transcriptional and post-transcriptional events trigger de novo infB expression in cold stressed Escherichia coli
por: Brandi, Anna, et al.
Publicado: (2019)

Timing of GTP binding and hydrolysis by translation termination factor RF3
por: Peske, Frank, et al.
Publicado: (2014)

Structure of the protein core of translation initiation factor 2 in apo, GTP-bound and GDP-bound forms
por: Simonetti, Angelita, et al.
Publicado: (2013)

Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A
por: Kaminishi, Tatsuya, et al.
Publicado: (2015)

Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation
por: Huang, Bridget Y., et al.
Publicado: (2020)

Initiation of mRNA translation in bacteria: structural and dynamic aspects
por: Gualerzi, Claudio O., et al.
Publicado: (2015)

Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways
por: López-Alonso, Jorge P., et al.
Publicado: (2017)

The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability
por: Roostalu, Johanna, et al.
Publicado: (2020)

Impact of methylations of m(2)G966/m(5)C967 in 16S rRNA on bacterial fitness and translation initiation
por: Burakovsky, Dmitry E., et al.
Publicado: (2012)

Dynamic clustering of dynamin-amphiphysin helices regulates membrane constriction and fission coupled with GTP hydrolysis
por: Takeda, Tetsuya, et al.
Publicado: (2018)

The role of GTP hydrolysis by EF-G in ribosomal translocation
por: Rexroad, Gillian, et al.
Publicado: (2022)

Cold-Responsive Regions of Paradigm Cold-Shock and Non-Cold-Shock mRNAs Responsible for Cold Shock Translational Bias
por: Giuliodori, Anna Maria, et al.
Publicado: (2019)

Codon usage and protein length-dependent feedback from translation elongation regulates translation initiation and elongation speed
por: Lyu, Xueliang, et al.
Publicado: (2021)

Disparate Phenotypes Resulting from Mutations of a Single Histidine in Switch II of Geobacillus stearothermophilus Translation Initiation Factor IF2
por: Tomsic, Jerneja, et al.
Publicado: (2020)

Termination of translation in eukaryotes is mediated by the quaternary eRF1•eRF3•GTP•Mg(2+) complex. The biological roles of eRF3 and prokaryotic RF3 are profoundly distinct
por: Mitkevich, Vladimir A., et al.
Publicado: (2006)

Distinct GDP/GTP bound states of the tandem G-domains of EngA regulate ribosome binding
por: Tomar, Sushil Kumar, et al.
Publicado: (2009)

Exploring potassium-dependent GTP hydrolysis in TEES family GTPases
por: Rafay, Abu, et al.
Publicado: (2012)

Unveiling the catalytic mechanism of GTP hydrolysis in microtubules
por: Beckett, Daniel, et al.
Publicado: (2023)

Alternative translation initiation augments the human mitochondrial proteome
por: Kazak, Lawrence, et al.
Publicado: (2013)

GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding
por: Kononenko, Artem V., et al.
Publicado: (2010)

The role of GTP in transient splitting of 70S ribosomes by RRF (ribosome recycling factor) and EF-G (elongation factor G)
por: Hirokawa, Go, et al.
Publicado: (2008)

A ribosomal RNA fragment with 2′,3′-cyclic phosphate and GTP-binding activity acts as RIG-I ligand
por: Jung, Stephanie, et al.
Publicado: (2020)

The Rap–RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues
por: Scrima, Andrea, et al.
Publicado: (2008)

Unique translation initiation of mRNAs-containing TISU element
por: Elfakess, Rofa, et al.
Publicado: (2011)

Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase γ replication fidelity
por: Pursell, Zachary F., et al.
Publicado: (2008)

Differential contribution of the m(7)G-cap to the 5′ end-dependent translation initiation of mammalian mRNAs
por: Andreev, Dmitri E., et al.
Publicado: (2009)

A novel mechanism of eukaryotic translation initiation that is neither m(7)G-cap-, nor IRES-dependent
por: Terenin, Ilya M., et al.
Publicado: (2013)

DPC29 promotes post-initiation mitochondrial translation in Saccharomyces cerevisiae
por: Hubble, Kyle A, et al.
Publicado: (2023)

USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1
por: Li, Zengxia, et al.
Publicado: (2018)

The initiation factor 3 (IF3) residues interacting with initiator tRNA elbow modulate the fidelity of translation initiation and growth fitness in Escherichia coli
por: Singh, Jitendra, et al.
Publicado: (2022)

Conformational Response of 30S-bound IF3 to A-Site Binders Streptomycin and Kanamycin
por: Chulluncuy, Roberto, et al.
Publicado: (2016)

Allosteric site variants affect GTP hydrolysis on Ras
por: Johnson, Christian W., et al.
Publicado: (2023)

Structural basis of IRGB10 oligomerization by GTP hydrolysis
por: Ha, Hyun Ji, et al.
Publicado: (2023)

Translation initiation factor eIF3 promotes programmed stop codon readthrough
por: Beznosková, Petra, et al.
Publicado: (2015)

Unidirectional constant rate motion of the ribosomal scanning particle during eukaryotic translation initiation
por: Vassilenko, Konstantin S., et al.
Publicado: (2011)

Rps5-Rps16 communication is essential for efficient translation initiation in yeast S. cerevisiae
por: Ghosh, Arnab, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bgpl4rl8blbbmsc3qla0nk5slc