Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells

Background: Information on the potential developmental toxicity (DT) of the majority of chemicals is scarce, and test capacities for further animal-based testing are limited. Therefore, new approaches with higher throughput are required. A screening strategy based on the use of relevant human cell t...

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Detalles Bibliográficos
Autores principales: Zimmer, Bastian, Lee, Gabsang, Balmer, Nina V, Meganathan, Kesavan, Sachinidis, Agapios, Studer, Lorenz, Leist, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440079/
https://www.ncbi.nlm.nih.gov/pubmed/22571897
http://dx.doi.org/10.1289/ehp.1104489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440079/
https://www.ncbi.nlm.nih.gov/pubmed/22571897
http://dx.doi.org/10.1289/ehp.1104489

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