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A Three-Stage Algorithm to Make Toxicologically Relevant Activity Calls from Quantitative High Throughput Screening Data
Background: The ability of a substance to induce a toxicological response is better understood by analyzing the response profile over a broad range of concentrations than at a single concentration. In vitro quantitative high throughput screening (qHTS) assays are multiple-concentration experiments w...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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National Institute of Environmental Health Sciences
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440085/ https://www.ncbi.nlm.nih.gov/pubmed/22575717 http://dx.doi.org/10.1289/ehp.1104688 |