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Profiling Environmental Chemicals for Activity in the Antioxidant Response Element Signaling Pathway Using a High Throughput Screening Approach

Background: Oxidative stress has been implicated in the pathogenesis of a variety of diseases ranging from cancer to neurodegeneration, highlighting the need to identify chemicals that can induce this effect. The antioxidant response element (ARE) signaling pathway plays an important role in the ame...

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Detalles Bibliográficos
Autores principales:	Shukla, Sunita J, Huang, Ruili, Simmons, Steven O, Tice, Raymond R, Witt, Kristine L, VanLeer, Danielle, Ramabhadran, Ram, Austin, Christopher P, Xia, Menghang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440086/ https://www.ncbi.nlm.nih.gov/pubmed/22551509 http://dx.doi.org/10.1289/ehp.1104709

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