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The mTOR Inhibitor Rapamycin Has Limited Acute Anticonvulsant Effects in Mice
OBJECTIVE: The mammalian target of rapamycin (mTOR) pathway integrates signals from different nutrient sources, including amino acids and glucose. Compounds that inhibit mTOR kinase activity such as rapamycin and everolimus can suppress seizures in some chronic animal models and in patients with tub...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440313/ https://www.ncbi.nlm.nih.gov/pubmed/22984623 http://dx.doi.org/10.1371/journal.pone.0045156 |