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The mTOR Inhibitor Rapamycin Has Limited Acute Anticonvulsant Effects in Mice

OBJECTIVE: The mammalian target of rapamycin (mTOR) pathway integrates signals from different nutrient sources, including amino acids and glucose. Compounds that inhibit mTOR kinase activity such as rapamycin and everolimus can suppress seizures in some chronic animal models and in patients with tub...

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Detalles Bibliográficos
Autores principales:	Hartman, Adam L., Santos, Polan, Dolce, Alison, Hardwick, J. Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440313/ https://www.ncbi.nlm.nih.gov/pubmed/22984623 http://dx.doi.org/10.1371/journal.pone.0045156

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