T Cell Responses Induced by Adenoviral Vectored Vaccines Can Be Adjuvanted by Fusion of Antigen to the Oligomerization Domain of C4b-Binding Protein

Viral vectored vaccines have been shown to induce both T cell and antibody responses in animals and humans. However, the induction of even higher level T cell responses may be crucial in achieving vaccine efficacy against difficult disease targets, especially in humans. Here we investigate the oligo...

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Detalles Bibliográficos
Autores principales: Forbes, Emily K., de Cassan, Simone C., Llewellyn, David, Biswas, Sumi, Goodman, Anna L., Cottingham, Matthew G., Long, Carole A., Pleass, Richard J., Hill, Adrian V. S., Hill, Fergal, Draper, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440343/
https://www.ncbi.nlm.nih.gov/pubmed/22984589
http://dx.doi.org/10.1371/journal.pone.0044943

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