Direct Chromatin PCR (DC-PCR): Hypotonic Conditions Allow Differentiation of Chromatin States during Thermal Cycling

Current methods to study chromatin configuration are not well suited for high throughput drug screening since they require large cell numbers and multiple experimental steps that include centrifugation for isolation of nuclei or DNA. Here we show that site specific chromatin analysis can be achieved...

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Detalles Bibliográficos
Autores principales: Vatolin, Sergei, Khan, Shahper N., Reu, Frederic J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440349/
https://www.ncbi.nlm.nih.gov/pubmed/22984542
http://dx.doi.org/10.1371/journal.pone.0044690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440349/
https://www.ncbi.nlm.nih.gov/pubmed/22984542
http://dx.doi.org/10.1371/journal.pone.0044690

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