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Polar/Ionizable Residues in Transmembrane Segments: Effects on Helix-Helix Packing
The vast majority of membrane proteins are anchored to biological membranes through hydrophobic α-helices. Sequence analysis of high-resolution membrane protein structures show that ionizable amino acid residues are present in transmembrane (TM) helices, often with a functional and/or structural rol...
Autores principales: | Bañó-Polo, Manuel, Baeza-Delgado, Carlos, Orzáez, Mar, Marti-Renom, Marc A., Abad, Concepción, Mingarro, Ismael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440369/ https://www.ncbi.nlm.nih.gov/pubmed/22984481 http://dx.doi.org/10.1371/journal.pone.0044263 |
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