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Dendritic Cells Control CD4(+)CD25(+) Treg Cell Suppressor Function In Vitro through Juxtacrine Delivery of IL-2
CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) restrict inflammatory responses to self and nonself. Aberrant Treg activity is pathologic: Insufficient Treg activity is implicated in autoimmunity, allergy, and graft-versus-host-disease; overabundant activity is implicated in chronic infection and c...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440416/ https://www.ncbi.nlm.nih.gov/pubmed/22984435 http://dx.doi.org/10.1371/journal.pone.0043609 |