An age-dependent reversal in the protective capacities of JNK signaling shortens Caenorhabditis elegans lifespan

Stress-activated protein kinase (SAPK) pathways are evolutionarily conserved signaling modules that orchestrate protective responses to adverse environmental conditions. However, under certain conditions, their activation can be deleterious. Thus, activation of the c-Jun N-terminal kinase (JNK) SAPK...

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Detalles Bibliográficos
Autores principales: Twumasi-Boateng, Kwame, Wang, Tim W, Tsai, Linda, Lee, Kuang-Hui, Salehpour, Ali, Bhat, Sudarshan, Tan, Man-Wah, Shapira, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440580/
https://www.ncbi.nlm.nih.gov/pubmed/22554143
http://dx.doi.org/10.1111/j.1474-9726.2012.00829.x

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