Short-term information processing, long-term responses: Insights by mathematical modeling of signal transduction: Early activation dynamics of key signaling mediators can be predictive for cell fate decisions

How do cells interpret information from their environment and translate it into specific cell fate decisions? We propose that cell fate is already encoded in early signaling events and thus can be predicted from defined signal properties. Specifically, we hypothesize that the time integral of activa...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneider, Annette, Klingmüller, Ursula, Schilling, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Insights & Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440590/
https://www.ncbi.nlm.nih.gov/pubmed/22528856
http://dx.doi.org/10.1002/bies.201100172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440590/
https://www.ncbi.nlm.nih.gov/pubmed/22528856
http://dx.doi.org/10.1002/bies.201100172

Ejemplares similares