Rationale for treating oedema in Duchenne muscular dystrophy with eplerenone

Recently we reported a cytoplasmic sodium overload to cause a severe osmotic oedema in Duchenne muscular dystrophy (DMD). Our results suggested that this dual overload of sodium ions and water precedes the dystrophic process and persists until fatty muscle degeneration is complete. The present paper...

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Detalles Bibliográficos
Autores principales: LEHMANN-HORN, FRANK, WEBER, MARC-ANDRÉ, NAGEL, ARMIN M., MEINCK, HANS-MICHAEL, BREITENBACH, SIMON, SCHARRER, JOHANNES, JURKAT-ROTT, KARIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore SpA 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440802/
https://www.ncbi.nlm.nih.gov/pubmed/22655515

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