Somatic Populations of PGT135–137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

Select HIV-1-infected individuals develop sera capable of neutralizing diverse viral strains. The molecular basis of this neutralization is currently being deciphered by the isolation of HIV-1-neutralizing antibodies. In one infected donor, three neutralizing antibodies, PGT135–137, were identified...

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Detalles Bibliográficos
Autores principales: Zhu, Jiang, O’Dell, Sijy, Ofek, Gilad, Pancera, Marie, Wu, Xueling, Zhang, Baoshan, Zhang, Zhenhai, Mullikin, James C., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441199/
https://www.ncbi.nlm.nih.gov/pubmed/23024643
http://dx.doi.org/10.3389/fmicb.2012.00315

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