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Epidemiology of Tick-Borne Borreliosis in Morocco
BACKGROUND: The presence in Morocco of Argasid ticks of the Ornithodoros erraticus complex, the vector of tick-borne relapsing fever (TBRF) in North Africa, has been known since 1919, but the disease is rarely diagnosed and few epidemiological data are available. METHODOLOGY/PRINCIPAL FINDINGS: Betw...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441398/ https://www.ncbi.nlm.nih.gov/pubmed/23029574 http://dx.doi.org/10.1371/journal.pntd.0001810 |
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author | Diatta, Georges Souidi, Yassine Granjon, Laurent Arnathau, Céline Durand, Patrick Chauvancy, Gilles Mané, Youssouph Sarih, M'hammed Belghyti, Driss Renaud, François Trape, Jean-François |
author_facet | Diatta, Georges Souidi, Yassine Granjon, Laurent Arnathau, Céline Durand, Patrick Chauvancy, Gilles Mané, Youssouph Sarih, M'hammed Belghyti, Driss Renaud, François Trape, Jean-François |
author_sort | Diatta, Georges |
collection | PubMed |
description | BACKGROUND: The presence in Morocco of Argasid ticks of the Ornithodoros erraticus complex, the vector of tick-borne relapsing fever (TBRF) in North Africa, has been known since 1919, but the disease is rarely diagnosed and few epidemiological data are available. METHODOLOGY/PRINCIPAL FINDINGS: Between 2006 and 2011, we investigated the presence of Ornithodoros ticks in rodent burrows in 34 sites distributed across Morocco. We also collected small mammals in 10 sites and we investigated TBRF in febrile patients in Kenitra district. The prevalence of Borrelia infections was assessed by nested PCR amplification in ticks and the brain tissue of small mammals, and by evaluation of thick blood films in patients. A high proportion of burrows were infested with ticks of the O. erraticus complex in all regions of Morocco, with a mean of 39.5% for the whole country. Borrelia infections were found in 39/382 (10.2%) of the ticks and 12/140 (8.6%) of the rodents and insectivores studied by PCR amplification, and 102 patients tested positive by thick blood film. Five small mammalian species were found infected: Dipodillus campestris, Meriones shawi, Gerbillus hoogstrali, Gerbillus occiduus and Atelerix algirus. Three Borrelia species were identified in ticks and/or rodents: B. hispanica, B. crocidurae and B. merionesi. CONCLUSIONS/SIGNIFICANCE: Tick populations belonging to O. erraticus complex are widely distributed in Morocco and a high proportion of ticks and small mammals are infected by Borrelia species. Although rarely diagnosed, TBRF may be a common cause of morbidity in all regions of Morocco. |
format | Online Article Text |
id | pubmed-3441398 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-34413982012-10-01 Epidemiology of Tick-Borne Borreliosis in Morocco Diatta, Georges Souidi, Yassine Granjon, Laurent Arnathau, Céline Durand, Patrick Chauvancy, Gilles Mané, Youssouph Sarih, M'hammed Belghyti, Driss Renaud, François Trape, Jean-François PLoS Negl Trop Dis Research Article BACKGROUND: The presence in Morocco of Argasid ticks of the Ornithodoros erraticus complex, the vector of tick-borne relapsing fever (TBRF) in North Africa, has been known since 1919, but the disease is rarely diagnosed and few epidemiological data are available. METHODOLOGY/PRINCIPAL FINDINGS: Between 2006 and 2011, we investigated the presence of Ornithodoros ticks in rodent burrows in 34 sites distributed across Morocco. We also collected small mammals in 10 sites and we investigated TBRF in febrile patients in Kenitra district. The prevalence of Borrelia infections was assessed by nested PCR amplification in ticks and the brain tissue of small mammals, and by evaluation of thick blood films in patients. A high proportion of burrows were infested with ticks of the O. erraticus complex in all regions of Morocco, with a mean of 39.5% for the whole country. Borrelia infections were found in 39/382 (10.2%) of the ticks and 12/140 (8.6%) of the rodents and insectivores studied by PCR amplification, and 102 patients tested positive by thick blood film. Five small mammalian species were found infected: Dipodillus campestris, Meriones shawi, Gerbillus hoogstrali, Gerbillus occiduus and Atelerix algirus. Three Borrelia species were identified in ticks and/or rodents: B. hispanica, B. crocidurae and B. merionesi. CONCLUSIONS/SIGNIFICANCE: Tick populations belonging to O. erraticus complex are widely distributed in Morocco and a high proportion of ticks and small mammals are infected by Borrelia species. Although rarely diagnosed, TBRF may be a common cause of morbidity in all regions of Morocco. Public Library of Science 2012-09-13 /pmc/articles/PMC3441398/ /pubmed/23029574 http://dx.doi.org/10.1371/journal.pntd.0001810 Text en © 2012 Diatta et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Diatta, Georges Souidi, Yassine Granjon, Laurent Arnathau, Céline Durand, Patrick Chauvancy, Gilles Mané, Youssouph Sarih, M'hammed Belghyti, Driss Renaud, François Trape, Jean-François Epidemiology of Tick-Borne Borreliosis in Morocco |
title | Epidemiology of Tick-Borne Borreliosis in Morocco |
title_full | Epidemiology of Tick-Borne Borreliosis in Morocco |
title_fullStr | Epidemiology of Tick-Borne Borreliosis in Morocco |
title_full_unstemmed | Epidemiology of Tick-Borne Borreliosis in Morocco |
title_short | Epidemiology of Tick-Borne Borreliosis in Morocco |
title_sort | epidemiology of tick-borne borreliosis in morocco |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441398/ https://www.ncbi.nlm.nih.gov/pubmed/23029574 http://dx.doi.org/10.1371/journal.pntd.0001810 |
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