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Biologically-Directed Modeling Reflects Cytolytic Clearance of SIV-Infected Cells In Vivo in Macaques
The disappointing outcomes of cellular immune-based vaccines against HIV-1 despite strong evidence for the protective role of CD8(+) T lymphocytes (CTLs) has prompted revisiting the mechanisms of cellular immunity. Prior data from experiments examining the kinetics of Simian Immunodeficiency Virus (...
Autores principales: | Wick, W. David, Yang, Otto O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441463/ https://www.ncbi.nlm.nih.gov/pubmed/23028619 http://dx.doi.org/10.1371/journal.pone.0044778 |
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