Elevated Urine Heparanase Levels Are Associated with Proteinuria and Decreased Renal Allograft Function

Heparanase is an endo-β-glucuronidase that cleaves heparan sulfate side chains, leading to structural modifications that loosen the extracellular matrix barrier and associated with tumor metastasis, inflammation and angiogenesis. In addition, the highly sulfated heparan sulfate proteoglycans are imp...

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Detalles Bibliográficos
Autores principales: Shafat, Itay, Agbaria, Amir, Boaz, Mona, Schwartz, Doron, Baruch, Ronny, Nakash, Richard, Ilan, Neta, Vlodavsky, Israel, Weinstein, Talia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441528/
https://www.ncbi.nlm.nih.gov/pubmed/23028487
http://dx.doi.org/10.1371/journal.pone.0044076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441528/
https://www.ncbi.nlm.nih.gov/pubmed/23028487
http://dx.doi.org/10.1371/journal.pone.0044076

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