Proteomic and Systems Biology Analysis of Monocytes Exposed to Securinine, a GABA(A) Receptor Antagonist and Immune Adjuvant

Securinine, a GABA(A) receptor antagonist, has been reported to enhance monocyte cell killing of Coxiella burnetii without obvious adverse effects in vivo. We employed multiplex 2D gel electrophoresis using Zdyes, a new generation of covalently linked fluorescent differential protein detection dyes...

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Detalles Bibliográficos
Autores principales: Shipman, Matt, Lubick, Kirk, Fouchard, David, Guram, Rajani, Grieco, Paul, Jutila, Mark, Dratz, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441550/
https://www.ncbi.nlm.nih.gov/pubmed/23028424
http://dx.doi.org/10.1371/journal.pone.0041278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441550/
https://www.ncbi.nlm.nih.gov/pubmed/23028424
http://dx.doi.org/10.1371/journal.pone.0041278

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