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A Predictive Framework for Integrating Disparate Genomic Data Types Using Sample-Specific Gene Set Enrichment Analysis and Multi-Task Learning

Understanding the root molecular and genetic causes driving complex traits is a fundamental challenge in genomics and genetics. Numerous studies have used variation in gene expression to understand complex traits, but the underlying genomic variation that contributes to these expression changes is n...

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Detalles Bibliográficos
Autores principales: Bennett, Brian D., Xiong, Qing, Mukherjee, Sayan, Furey, Terrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441565/
https://www.ncbi.nlm.nih.gov/pubmed/23028573
http://dx.doi.org/10.1371/journal.pone.0044635