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Wnt Activation by Wild Type and Mutant Myocilin in Cultured Human Trabecular Meshwork Cells
BACKGROUND: Myocilin is a gene linked to the most prevalent form of glaucoma, a major blinding disease. The trabecular meshwork (TM), a specialized eye tissue, is believed to be involved, at least in part, in the development of glaucoma. The Pro(370) to Leu (P370L) mutation of myocilin is associated...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441605/ https://www.ncbi.nlm.nih.gov/pubmed/23028669 http://dx.doi.org/10.1371/journal.pone.0044902 |