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PDGF Receptor-α Does Not Promote HCMV Entry into Epithelial and Endothelial Cells but Increased Quantities Stimulate Entry by an Abnormal Pathway
Epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor-α (PDGFRα) were reported to mediate entry of HCMV, including HCMV lab strain AD169. AD169 cannot assemble gH/gL/UL128–131, a glycoprotein complex that is essential for HCMV entry into biologically important epithelia...
Autores principales: | Vanarsdall, Adam L., Wisner, Todd W., Lei, Hetian, Kazlauskas, Andrius, Johnson, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441672/ https://www.ncbi.nlm.nih.gov/pubmed/23028311 http://dx.doi.org/10.1371/journal.ppat.1002905 |
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