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PDGF Receptor-α Does Not Promote HCMV Entry into Epithelial and Endothelial Cells but Increased Quantities Stimulate Entry by an Abnormal Pathway

Epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor-α (PDGFRα) were reported to mediate entry of HCMV, including HCMV lab strain AD169. AD169 cannot assemble gH/gL/UL128–131, a glycoprotein complex that is essential for HCMV entry into biologically important epithelia...

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Detalles Bibliográficos
Autores principales: Vanarsdall, Adam L., Wisner, Todd W., Lei, Hetian, Kazlauskas, Andrius, Johnson, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441672/
https://www.ncbi.nlm.nih.gov/pubmed/23028311
http://dx.doi.org/10.1371/journal.ppat.1002905

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