Functional Variants in NFKBIE and RTKN2 Involved in Activation of the NF-κB Pathway Are Associated with Rheumatoid Arthritis in Japanese

Rheumatoid arthritis is an autoimmune disease with a complex etiology, leading to inflammation of synovial tissue and joint destruction. Through a genome-wide association study (GWAS) and two replication studies in the Japanese population (7,907 cases and 35,362 controls), we identified two gene loc...

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Detalles Bibliográficos
Autores principales: Myouzen, Keiko, Kochi, Yuta, Okada, Yukinori, Terao, Chikashi, Suzuki, Akari, Ikari, Katsunori, Tsunoda, Tatsuhiko, Takahashi, Atsushi, Kubo, Michiaki, Taniguchi, Atsuo, Matsuda, Fumihiko, Ohmura, Koichiro, Momohara, Shigeki, Mimori, Tsuneyo, Yamanaka, Hisashi, Kamatani, Naoyuki, Yamada, Ryo, Nakamura, Yusuke, Yamamoto, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441678/
https://www.ncbi.nlm.nih.gov/pubmed/23028356
http://dx.doi.org/10.1371/journal.pgen.1002949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441678/
https://www.ncbi.nlm.nih.gov/pubmed/23028356
http://dx.doi.org/10.1371/journal.pgen.1002949

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