Cargando…

Development of Skewed Functionality of HIV-1-Specific Cytotoxic CD8(+) T Cells from Primary to Early Chronic Phase of HIV Infection

In recent years, the prevalence of HIV-1 infection has been rapidly increasing among men who have sex with men (MSM). However, it remains unknown how the host immune system responds to the infection in this population. We assessed the quantity of HIV-specific CD8(+) T-cell responses by using Elispot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Wanhai, Qiu, Chenli, Qiu, Chao, Wang, Ying, Zhang, Xiaoyan, Xu, Jianqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441698/ https://www.ncbi.nlm.nih.gov/pubmed/23028721 http://dx.doi.org/10.1371/journal.pone.0044983

Ejemplares similares

Early Skewed Distribution of Total and HIV-Specific CD8(+) T-Cell Memory Phenotypes during Primary HIV Infection Is Related to Reduced Antiviral Activity and Faster Disease Progression
por: Ghiglione, Yanina, et al.
Publicado: (2014)

Immune Signature of Enhanced Functional Avidity CD8(+) T Cells in vivo Induced by Vaccinia Vectored Vaccine
por: Hu, Zhidong, et al.
Publicado: (2017)

CD160 Plays a Protective Role During Chronic Infection by Enhancing Both Functionalities and Proliferative Capacity of CD8+ T Cells
por: Zhang, Linxia, et al.
Publicado: (2020)

Immune Activation Influences SAMHD1 Expression and Vpx-mediated SAMHD1 Degradation during Chronic HIV-1 Infection
por: Fu, Weihui, et al.
Publicado: (2016)

Potential Role for HIV-Specific CD38(−)/HLA-DR(+) CD8(+) T Cells in Viral Suppression and Cytotoxicity in HIV Controllers
por: Hua, Stéphane, et al.
Publicado: (2014)

The potential role of HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppressive activity and cytotoxicity in HIV controllers
por: Hua, Stéphane, et al.
Publicado: (2014)

Selective miRNA inhibition in CD8(+) cytotoxic T lymphocytes enhances HIV-1 specific cytotoxic responses
por: Madrid-Elena, Nadia, et al.
Publicado: (2022)

P16-31. Skewed HIV-1-specific CD4+ Th2 helper cell contribution in progressive HIV-1 infection
por: Chevalier, M, et al.
Publicado: (2009)

Improving the ex vivo expansion of human tumor-reactive CD8 + T cells by targeting toll-like receptors
por: Qiu, Chenli, et al.
Publicado: (2022)

Phenotypic Characterization of HIV-Specific CD8(+) T Cells during Early and Chronic Infant HIV-1 Infection
por: Slyker, Jennifer A., et al.
Publicado: (2011)

Hsa-miR-31 Governs T-Cell Homeostasis in HIV Protection via IFN-γ-Stat1-T-Bet Axis
por: Zhu, Lingyan, et al.
Publicado: (2021)

Enhanced normalisation of CD4/CD8 ratio with early antiretroviral therapy in primary HIV infection
por: Thornhill, John, et al.
Publicado: (2014)

Design and validation of HIV peptide pools for detection of HIV-specific CD4(+) and CD8(+) T cells
por: Al-kolla, Rita, et al.
Publicado: (2022)

Role of HIV-specific CD8(+) T cells in pediatric HIV cure strategies after widespread early viral escape
por: Leitman, Ellen M., et al.
Publicado: (2017)

Tim-3 Negatively Regulates Cytotoxicity in Exhausted CD8(+) T Cells in HIV Infection
por: Sakhdari, Ali, et al.
Publicado: (2012)

Transcriptomic Assay of CD8(+) T Cells in Treatment-Naïve HIV, HCV-Mono-Infected and HIV/HCV-Co-Infected Chinese
por: Zhao, Jin, et al.
Publicado: (2012)

Early changes in the CD8 T Cell immunodominance hierarchy in primary HIV infection prior to seroconversion
por: Keane, N, et al.
Publicado: (2012)

HIV-Specific CD8(+) T Lymphocytes in Blood of Long-Term HIV-Infected Hemophilia Patients
por: Daniel, Volker, et al.
Publicado: (2013)

HIV-1-Specific CD11c(+) CD8(+) T Cells Display Low PD-1 Expression and Strong Anti-HIV-1 Activity
por: Guo, An-Liang, et al.
Publicado: (2021)

Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8(+) T cells
por: Wang, Zhongfang, et al.
Publicado: (2015)

The CD8 and CD4 T-Cell Response against Kaposi's Sarcoma-Associated Herpesvirus Is Skewed Towards Early and Late Lytic Antigens
por: Robey, Rebecca C., et al.
Publicado: (2009)

A Single HIV-1 Cluster and a Skewed Immune Homeostasis Drive the Early Spread of HIV among Resting CD4+ Cell Subsets within One Month Post-Infection
por: Bacchus, Charline, et al.
Publicado: (2013)

Loss of HIV-1–specific CD8(+) T Cell Proliferation after Acute HIV-1 Infection and Restoration by Vaccine-induced HIV-1–specific CD4(+) T Cells
por: Lichterfeld, Mathias, et al.
Publicado: (2004)

Differential Compartmentalization of HIV-Targeting Immune Cells in Inner and Outer Foreskin Tissue
por: Liu, Aiping, et al.
Publicado: (2014)

HIV-1 protective epitope-specific CD8(+) T cells in HIV-1-exposed seronegative individuals
por: Chikata, Takayuki, et al.
Publicado: (2023)

0A07-01. HIV-specific CD8(+ )T-cells of vaccinees exhibit proliferative and cytotoxic capacities comparable to those of progressors
por: Rood, JE, et al.
Publicado: (2009)

Control of HIV-1 by multiple immunodominant HIV-1-specific CD8+ T cells in HIV-1-infected Japanese individuals
por: Murakoshi, H, et al.
Publicado: (2012)

Substantial Differences in Specificity of HIV-Specific Cytotoxic T Cells in Acute and Chronic HIV Infection
por: Goulder, Philip J.R., et al.
Publicado: (2001)

TCF-1 regulates HIV-specific CD8(+) T cell expansion capacity
por: Rutishauser, Rachel L., et al.
Publicado: (2021)

Abundance of Early Functional HIV-Specific CD8(+) T Cells Does Not Predict AIDS-Free Survival Time
por: Schellens, Ingrid M. M., et al.
Publicado: (2008)

Allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv enhance specific cytotoxic activity against HIV Env(+) cells invivo
por: Pan, Hanyu, et al.
Publicado: (2023)

Impact of T(h)1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques
por: Verma, Anil, et al.
Publicado: (2020)

Identification of miRNA-mRNA crosstalk in CD4(+) T cells during HIV-1 infection by integrating transcriptome analyses
por: Liao, Qibin, et al.
Publicado: (2017)

Th17 and Th17/Treg ratio at early HIV infection associate with protective HIV-specific CD8(+) T-cell responses and disease progression
por: Falivene, Juliana, et al.
Publicado: (2015)

Oligoclonal Expansions of CD8(+) T Cells in Chronic HIV Infection Are Antigen Specific
por: Wilson, Jamie D.K., et al.
Publicado: (1998)

Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection
por: Das, Abhishek, et al.
Publicado: (2008)

Persistent expansion and Th1-like skewing of HIV-specific circulating T follicular helper cells during antiretroviral therapy
por: Niessl, Julia, et al.
Publicado: (2020)

Correction to: Identification of miRNA-mRNA crosstalk in CD4(+) T cells during HIV-1 infection by integrating transcriptome analyses
por: Liao, Qibin, et al.
Publicado: (2020)

Early HIV-1 Envelope-specific Cytotoxic T Lymphocyte Responses in Vertically Infected Infants
por: Pikora, Cheryl A., et al.
Publicado: (1997)

Robust HIV-specific CD4(+) and CD8(+) T-cell responses distinguish elite control in adolescents living with HIV from viremic nonprogressors
por: Vieira, Vinicius A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qj1b9jklmf86rokkbb285o2gpi