Molecular Basis for Nucleotide Conservation at the Ends of the Dengue Virus Genome

The dengue virus (DV) is an important human pathogen from the Flavivirus genus, whose genome- and antigenome RNAs start with the strictly conserved sequence pppAG. The RNA-dependent RNA polymerase (RdRp), a product of the NS5 gene, initiates RNA synthesis de novo, i.e., without the use of a pre-exis...

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Detalles Bibliográficos
Autores principales: Selisko, Barbara, Potisopon, Supanee, Agred, Rym, Priet, Stéphane, Varlet, Isabelle, Thillier, Yann, Sallamand, Corinne, Debart, Françoise, Vasseur, Jean-Jacques, Canard, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441707/
https://www.ncbi.nlm.nih.gov/pubmed/23028313
http://dx.doi.org/10.1371/journal.ppat.1002912

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