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Association Test Based on SNP Set: Logistic Kernel Machine Based Test vs. Principal Component Analysis

GWAS has facilitated greatly the discovery of risk SNPs associated with complex diseases. Traditional methods analyze SNP individually and are limited by low power and reproducibility since correction for multiple comparisons is necessary. Several methods have been proposed based on grouping SNPs in...

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Detalles Bibliográficos
Autores principales:	Zhao, Yang, Chen, Feng, Zhai, Rihong, Lin, Xihong, Diao, Nancy, Christiani, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441747/ https://www.ncbi.nlm.nih.gov/pubmed/23028716 http://dx.doi.org/10.1371/journal.pone.0044978

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