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Synthetic genistein derivatives as modulators of glycosaminoglycan storage

BACKGROUND: Mucopolysaccharidoses (MPS) are severe metabolic disorders caused by accumulation of undegraded glycosaminoglycans (GAGs) in lysosomes due to defects in certain lysosomal hydrolases. Substrate reduction therapy (SRT) has been proposed as one of potential treatment procedures of MPS. Impo...

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Detalles Bibliográficos
Autores principales:	Kloska, Anna, Narajczyk, Magdalena, Jakóbkiewicz-Banecka, Joanna, Grynkiewicz, Grzegorz, Szeja, Wiesław, Gabig-Cimińska, Magdalena, Węgrzyn, Grzegorz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441846/ https://www.ncbi.nlm.nih.gov/pubmed/22846663 http://dx.doi.org/10.1186/1479-5876-10-153

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