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IgG-Fc glycoengineering in non-mammalian expression hosts
The remarkable success of therapeutic applications of immunoglobulin G (IgG) in form of monoclonal antibodies and pooled immunoglobulin G preparations has directed attention to this class of glycoproteins. It is commonly appreciated that oligosaccharides attached to the Fc-region play a critical rol...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442181/ https://www.ncbi.nlm.nih.gov/pubmed/22634260 http://dx.doi.org/10.1016/j.abb.2012.05.011 |