Quiescent fibroblasts are protected from proteasome inhibition–mediated toxicity

Proteasome inhibition is used as a treatment strategy for multiple types of cancers. Although proteasome inhibition can induce apoptotic cell death in actively proliferating cells, it is less effective in quiescent cells. In this study, we used primary human fibroblasts as a model system to explore...

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Detalles Bibliográficos
Autores principales: Legesse-Miller, Aster, Raitman, Irene, Haley, Erin M., Liao, Albert, Sun, Lova L., Wang, David J., Krishnan, Nithya, Lemons, Johanna M. S., Suh, Eric J., Johnson, Elizabeth L., Lund, Benjamin A., Coller, Hilary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442405/
https://www.ncbi.nlm.nih.gov/pubmed/22875985
http://dx.doi.org/10.1091/mbc.E12-03-0192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442405/
https://www.ncbi.nlm.nih.gov/pubmed/22875985
http://dx.doi.org/10.1091/mbc.E12-03-0192

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