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CIN85 phosphorylation is essential for EGFR ubiquitination and sorting into multivesicular bodies

Ubiquitination of the epidermal growth factor receptor (EGFR) by cbl and its cognate adaptor cbl-interacting protein of 85 kDa (CIN85) is known to play an essential role in directing this receptor to the lysosome for degradation. The mechanisms by which this ubiquitin modification is regulated are n...

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Detalles Bibliográficos
Autores principales:	Schroeder, Barbara, Srivatsan, Subhashini, Shaw, Andrey, Billadeau, Daniel, McNiven, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442408/ https://www.ncbi.nlm.nih.gov/pubmed/22833562 http://dx.doi.org/10.1091/mbc.E11-08-0666

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