GATA-6 promotes cell survival by up-regulating BMP-2 expression during embryonic stem cell differentiation

GATA-6 is a zinc-finger transcription factor essential for early embryogenesis. Ablation of GATA-6 in mice impairs endoderm differentiation and causes apoptosis of epiblast cells. The endoderm defects have been attributed to the loss of HNF4, disabled-2, and GATA-4. However, the mechanisms underlyin...

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Detalles Bibliográficos
Autores principales: Rong, Li, Liu, Jie, Qi, Yanmei, Graham, Alan M., Parmacek, Michael S., Li, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442421/
https://www.ncbi.nlm.nih.gov/pubmed/22855527
http://dx.doi.org/10.1091/mbc.E12-04-0313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442421/
https://www.ncbi.nlm.nih.gov/pubmed/22855527
http://dx.doi.org/10.1091/mbc.E12-04-0313

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