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Palmitoylation regulates vesicular trafficking of R-Ras to membrane ruffles and effects on ruffling and cell spreading

In this study we investigated the dynamics of R-Ras intracellular trafficking and its contributions to the unique roles of R-Ras in membrane ruffling and cell spreading. Wild type and constitutively active R-Ras localized to membranes of both Rab11- and transferrin-positive and -negative vesicles, w...

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Detalles Bibliográficos
Autores principales: Wurtzel, Jeremy G.T., Kumar, Puneet, Goldfinger, Lawrence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442799/
https://www.ncbi.nlm.nih.gov/pubmed/22751447
http://dx.doi.org/10.4161/sgtp.21084