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Palmitoylation regulates vesicular trafficking of R-Ras to membrane ruffles and effects on ruffling and cell spreading
In this study we investigated the dynamics of R-Ras intracellular trafficking and its contributions to the unique roles of R-Ras in membrane ruffling and cell spreading. Wild type and constitutively active R-Ras localized to membranes of both Rab11- and transferrin-positive and -negative vesicles, w...
Autores principales: | Wurtzel, Jeremy G.T., Kumar, Puneet, Goldfinger, Lawrence E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442799/ https://www.ncbi.nlm.nih.gov/pubmed/22751447 http://dx.doi.org/10.4161/sgtp.21084 |
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