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A shortcut from GPCR signaling to Rac-mediated actin cytoskeleton through an ELMO/DOCK complex

Chemotaxis, chemoattractant-guided directional cell migration, plays major roles in human innate immunity and in development of a model organism Dictyostelium discoideum. Human leukocytes and D. disscoideum share remarkable similarities in the molecular mechanisms that control chemotaxis. These cell...

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Detalles Bibliográficos
Autores principales: Xu, Xuehua, Jin, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442806/
https://www.ncbi.nlm.nih.gov/pubmed/22647486
http://dx.doi.org/10.4161/sgtp.20271