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A shortcut from GPCR signaling to Rac-mediated actin cytoskeleton through an ELMO/DOCK complex
Chemotaxis, chemoattractant-guided directional cell migration, plays major roles in human innate immunity and in development of a model organism Dictyostelium discoideum. Human leukocytes and D. disscoideum share remarkable similarities in the molecular mechanisms that control chemotaxis. These cell...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442806/ https://www.ncbi.nlm.nih.gov/pubmed/22647486 http://dx.doi.org/10.4161/sgtp.20271 |