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Effect of KRAS codon13 mutations in patients with advanced colorectal cancer (advanced CRC) under oxaliplatin containing chemotherapy. Results from a translational study of the AIO colorectal study group

BACKGROUND: To evaluate the value of KRAS codon 13 mutations in patients with advanced colorectal cancer (advanced CRC) treated with oxaliplatin and fluoropyrimidines. METHODS: Tumor specimens from 201 patients with advanced CRC from a randomized, phase III trial comparing oxaliplatin/5-FU vs. oxali...

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Detalles Bibliográficos
Autores principales:	Reinacher-Schick, Anke, Schulmann, Karsten, Modest, Dominik P, Bruns, Nina, Graeven, Ulrich, Jaworska, Malgorzata, Greil, Richard, Porschen, Rainer, Arnold, Dirk, Schmiegel, Wolff, Tannapfel, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442969/ https://www.ncbi.nlm.nih.gov/pubmed/22876876 http://dx.doi.org/10.1186/1471-2407-12-349

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