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Effect of KRAS codon13 mutations in patients with advanced colorectal cancer (advanced CRC) under oxaliplatin containing chemotherapy. Results from a translational study of the AIO colorectal study group
BACKGROUND: To evaluate the value of KRAS codon 13 mutations in patients with advanced colorectal cancer (advanced CRC) treated with oxaliplatin and fluoropyrimidines. METHODS: Tumor specimens from 201 patients with advanced CRC from a randomized, phase III trial comparing oxaliplatin/5-FU vs. oxali...
Autores principales: | Reinacher-Schick, Anke, Schulmann, Karsten, Modest, Dominik P, Bruns, Nina, Graeven, Ulrich, Jaworska, Malgorzata, Greil, Richard, Porschen, Rainer, Arnold, Dirk, Schmiegel, Wolff, Tannapfel, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442969/ https://www.ncbi.nlm.nih.gov/pubmed/22876876 http://dx.doi.org/10.1186/1471-2407-12-349 |
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