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The immunosuppressive factors IL-10, TGF-β, and VEGF do not affect the antigen-presenting function of CD40-activated B cells

BACKGROUND: Progress in recent years strengthened the concept of cellular tumor vaccinations. However, a crucial barrier to successful cancer immunotherapy is tumor-mediated immunosuppression. Tumor-derived soluble factors such as IL-10, TGF-β, and VEGF suppress effector cells either directly or ind...

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Detalles Bibliográficos
Autores principales:	Shimabukuro-Vornhagen, Alexander, Draube, Andreas, Liebig, Tanja M, Rothe, Achim, Kochanek, Matthias, von Bergwelt-Baildon, Michael S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443023/ https://www.ncbi.nlm.nih.gov/pubmed/22592077 http://dx.doi.org/10.1186/1756-9966-31-47

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