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Efficient Production of an Engineered Apoptin from Chicken Anemia Virus in a Recombinant E. coli for Tumor Therapeutic Applications
BACKGROUND: Apoptin, a nonstructural protein encoded by the VP3 gene of chicken anemia virus (CAV), has been shown to not only induce apoptosis when introduced into the precursors of chicken thymocytes, but has been found to specifically kill human cancer cells, tumor cell and transformed cells with...
Autores principales: | Lee, Meng-Shiou, Sun, Fang-Chun, Huang, Chi-Hung, Lien, Yi-Yang, Feng, Shin-Huei, Lai, Guan-Hua, Lee, Meng-Shiunn, Chao, Jung, Chen, Hsi-Jien, Tzen, Jason T C, Cheng, Hao-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443062/ https://www.ncbi.nlm.nih.gov/pubmed/22672291 http://dx.doi.org/10.1186/1472-6750-12-27 |
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