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Down-weighting overlapping genes improves gene set analysis
BACKGROUND: The identification of gene sets that are significantly impacted in a given condition based on microarray data is a crucial step in current life science research. Most gene set analysis methods treat genes equally, regardless how specific they are to a given gene set. RESULTS: In this wor...
Autores principales: | Tarca, Adi Laurentiu, Draghici, Sorin, Bhatti, Gaurav, Romero, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443069/ https://www.ncbi.nlm.nih.gov/pubmed/22713124 http://dx.doi.org/10.1186/1471-2105-13-136 |
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