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Kinin B(1) Receptor in Adipocytes Regulates Glucose Tolerance and Predisposition to Obesity
BACKGROUND: Kinins participate in the pathophysiology of obesity and type 2 diabetes by mechanisms which are not fully understood. Kinin B(1) receptor knockout mice (B(1) (−/−)) are leaner and exhibit improved insulin sensitivity. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that kinin B(1) receptor...
Autores principales: | Mori, Marcelo A., Sales, Vicência Micheline, Motta, Fabiana Louise, Fonseca, Raphael Gomes, Alenina, Natalia, Guadagnini, Dioze, Schadock, Ines, Silva, Elton Dias, Torres, Hugo A. M., dos Santos, Edson Lucas, Castro, Charlles Heldan, D’Almeida, Vânia, Andreotti, Sandra, Campaña, Amanda Baron, Sertié, Rogério A. L., Saad, Mario J. A., Lima, Fabio Bessa, Bader, Michael, Pesquero, João Bosco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443087/ https://www.ncbi.nlm.nih.gov/pubmed/23024762 http://dx.doi.org/10.1371/journal.pone.0044782 |
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