Cargando…
Skeletal Muscle Growth Hormone Receptor Signaling Regulates Basal, but Not Fasting-Induced, Lipid Oxidation
BACKGROUND: Growth hormone (GH) stimulates whole-body lipid oxidation, but its regulation of muscle lipid oxidation is not clearly defined. Mice with a skeletal muscle-specific knockout of the GH receptor (mGHRKO model) are protected from high fat diet (HFD)–induced insulin resistance and display in...
Autores principales: | Vijayakumar, Archana, Wu, YingJie, Buffin, Nicholas J., Li, Xiaosong, Sun, Hui, Gordon, Ronald E., Yakar, Shoshana, LeRoith, Derek |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443095/ https://www.ncbi.nlm.nih.gov/pubmed/23024761 http://dx.doi.org/10.1371/journal.pone.0044777 |
Ejemplares similares
-
The Intricate Role of Growth Hormone in Metabolism
por: Vijayakumar, Archana, et al.
Publicado: (2011) -
Targeted Loss of GHR Signaling in Mouse Skeletal Muscle Protects Against High-Fat Diet–Induced Metabolic Deterioration
por: Vijayakumar, Archana, et al.
Publicado: (2012) -
Insulin-Sensitizing Therapy Attenuates Type 2 Diabetes–Mediated Mammary Tumor Progression
por: Fierz, Yvonne, et al.
Publicado: (2010) -
Inhibiting PI3K reduces mammary tumor growth and induces hyperglycemia in a mouse model of insulin resistance and hyperinsulinemia
por: Gallagher, Emily Jane, et al.
Publicado: (2011) -
High-Efficient FLPo Deleter Mice in C57BL/6J Background
por: Wu, Yingjie, et al.
Publicado: (2009)