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Evolution of Bombesin Conjugates for Targeted PET Imaging of Tumors
Bombesin receptors are under intense investigation as molecular targets since they are overexpressed in several prevalent solid tumors. We rationally designed and synthesized a series of modified bombesin (BN) peptide analogs to study the influence of charge and spacers at the N-terminus, as well as...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443097/ https://www.ncbi.nlm.nih.gov/pubmed/23024746 http://dx.doi.org/10.1371/journal.pone.0044046 |