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Evolution of Bombesin Conjugates for Targeted PET Imaging of Tumors

Bombesin receptors are under intense investigation as molecular targets since they are overexpressed in several prevalent solid tumors. We rationally designed and synthesized a series of modified bombesin (BN) peptide analogs to study the influence of charge and spacers at the N-terminus, as well as...

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Detalles Bibliográficos
Autores principales:	Zhang, Hanwen, Abiraj, Keelara, Thorek, Daniel L. J., Waser, Beatrice, Smith-Jones, Peter M., Honer, Michael, Reubi, Jean Claude, Maecke, Helmut R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443097/ https://www.ncbi.nlm.nih.gov/pubmed/23024746 http://dx.doi.org/10.1371/journal.pone.0044046

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