Serine 162, an Essential Residue for the Mitochondrial Localization, Stability and Anti-Apoptotic Function of Mcl-1

Mcl-1 is an anti-apoptotic member of the Bcl-2 family that plays a key role in normal development, but also in pathologies such as cancer. It has some unusual properties compared to other anti-apoptotic members of the Bcl-2 family, and its expression and function are dynamically regulated by a varie...

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Detalles Bibliográficos
Autores principales: Thomas, Luke W., Lam, Connie, Clark, Richard E., White, Michael R. H., Spiller, David G., Moots, Robert J., Edwards, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443205/
https://www.ncbi.nlm.nih.gov/pubmed/23024798
http://dx.doi.org/10.1371/journal.pone.0045088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443205/
https://www.ncbi.nlm.nih.gov/pubmed/23024798
http://dx.doi.org/10.1371/journal.pone.0045088

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