Cargando…

Acid Sphingomyelinase Gene Knockout Ameliorates Hyperhomocysteinemic Glomerular Injury in Mice Lacking Cystathionine-β-Synthase

Acid sphingomyelinase (ASM) has been implicated in the development of hyperhomocysteinemia (hHcys)-induced glomerular oxidative stress and injury. However, it remains unknown whether genetically engineering of ASM gene produces beneficial or detrimental action on hHcys-induced glomerular injury. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boini, Krishna M., Xia, Min, Abais, Justine M., Xu, Ming, Li, Cai-xia, Li, Pin-Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443210/ https://www.ncbi.nlm.nih.gov/pubmed/23024785 http://dx.doi.org/10.1371/journal.pone.0045020

Ejemplares similares

Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene
por: Boini, Krishna M., et al.
Publicado: (2016)

Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes
por: Xiong, Jing, et al.
Publicado: (2013)

Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia
por: Koka, Saisudha, et al.
Publicado: (2017)

Implication of CD38 gene in podocyte epithelial-to-mesenchymal transition and glomerular sclerosis
por: Boini, Krishna M, et al.
Publicado: (2012)

Requirement of translocated lysosomal V1 H(+)-ATPase for activation of membrane acid sphingomyelinase and raft clustering in coronary endothelial cells
por: Xu, Ming, et al.
Publicado: (2012)

Cardioprotective potential of simvastatin in the hyperhomocysteinemic rat heart
por: Rohilla, Ankur, et al.
Publicado: (2012)

Cystathionine β-Synthase in Physiology and Cancer
por: Zhu, Haoran, et al.
Publicado: (2018)

Chemical and biomechanical characterization of hyperhomocysteinemic bone disease in an animal model
por: Massé, Priscilla G, et al.
Publicado: (2003)

Genistein Attenuates Vascular Endothelial Impairment in Ovariectomized Hyperhomocysteinemic Rats
por: Zhen, Panpan, et al.
Publicado: (2012)

Enhanced Expression of Cystathionine β-Synthase and Cystathionine γ-Lyase During Acute Cholecystitis-Induced Gallbladder Inflammation
por: Zhang, Li, et al.
Publicado: (2013)

Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
por: Morris, Andrew A. M., et al.
Publicado: (2016)

Cystathionine β-Synthase Regulates the Proliferation, Migration, and Invasion of Thyroid Carcinoma Cells
por: Jiang, Qi-Ying, et al.
Publicado: (2022)

Expression of Cystathionine β-synthase and Cystathionine γ-lyase in Human Pregnant Myometrium and Their Roles in the Control of Uterine Contractility
por: You, Xing-Ji, et al.
Publicado: (2011)

Antihyperhomocysteinemic and antihyperlipidemic effect of Trichilia connaroides in methionine-induced hyperhomocysteinemic animals
por: Prasanna, G.S., et al.
Publicado: (2011)

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)
por: Asimakopoulou, Antonia, et al.
Publicado: (2013)

Pioglitazone ameliorates glomerular NLRP3 inflammasome activation in apolipoprotein E knockout mice with diabetes mellitus
por: Wang, Yao, et al.
Publicado: (2017)

Vascular presentation of cystathionine beta-synthase deficiency in adulthood
por: Magner, Martin, et al.
Publicado: (2010)

Cystathionine β-Synthase Is Necessary for Axis Development in Vivo
por: Prabhudesai, Shubhangi, et al.
Publicado: (2018)

Association of Cystathionine β-Synthase Gene Polymorphisms With Preeclampsia
por: de León Bautista, Mercedes Piedad, et al.
Publicado: (2018)

Cystathionine-β-synthase: Molecular Regulation and Pharmacological Inhibition
por: Zuhra, Karim, et al.
Publicado: (2020)

Transcriptome analysis alk-SMase knockout mice reveals the effect of alkaline sphingomyelinase on liver
por: Zhu, Jiang, et al.
Publicado: (2022)

Downregulation of cystathionine β‐synthase and cystathionine γ‐lyase expression stimulates inflammation in kidney ischemia–reperfusion injury
por: Wang, Pengqi, et al.
Publicado: (2014)

Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase
por: Ahmad, Akbar, et al.
Publicado: (2016)

Brain Phenotype of Transgenic Mice Overexpressing Cystathionine β-Synthase
por: Régnier, Vinciane, et al.
Publicado: (2012)

Palm Tocotrienol-Rich Fraction Improves Vascular Proatherosclerotic Changes in Hyperhomocysteinemic Rats
por: Norsidah, Ku-Zaifah, et al.
Publicado: (2013)

Chemical chaperone rescue of mutant human cystathionine β-synthase
por: Singh, Laishram R., et al.
Publicado: (2007)

Cystathionine Beta-Synthase Deficiency Causes Fat Loss in Mice
por: Gupta, Sapna, et al.
Publicado: (2011)

Domain Organization, Catalysis and Regulation of Eukaryotic Cystathionine Beta-Synthases
por: Majtan, Tomas, et al.
Publicado: (2014)

Cystathionine beta synthase modulates senescence of human endothelial cells
por: Albertini, Eva, et al.
Publicado: (2012)

Role of cystathionine beta synthase in lipid metabolism in ovarian cancer
por: Chakraborty, Prabir K., et al.
Publicado: (2015)

Corrigendum: Cystathionine β-Synthase Is Necessary for Axis Development in vivo
por: Prabhudesai, Shubhangi, et al.
Publicado: (2018)

Heme-Thiolate Perturbation in Cystathionine β-Synthase by Mercury Compounds
por: Benchoam, Dayana, et al.
Publicado: (2021)

Emerging roles of cystathionine β-synthase in various forms of cancer
por: Ascenção, Kelly, et al.
Publicado: (2022)

H(2)S and homocysteine control a novel feedback regulation of cystathionine beta synthase and cystathionine gamma lyase in cardiomyocytes
por: Nandi, Shyam Sundar, et al.
Publicado: (2017)

Acid Sphingomyelinase Deficiency Ameliorates Farber Disease
por: Beckmann, Nadine, et al.
Publicado: (2019)

Analysis of MTHFR, CBS, Glutathione, Taurine, and Hydrogen Sulfide Levels in Retinas of Hyperhomocysteinemic Mice
por: Cui, Xuezhi, et al.
Publicado: (2017)

Down-Regulated Expression of Cystathionine β-Synthase and Cystathionine γ-Lyase in Varicocele, and Infertile Men: A Case-Control Study
por: Akbarian, Fahimeh, et al.
Publicado: (2022)

Correlation between cystathionine β-synthase T883C genetic polymorphism and primary hypertension
por: ZHANG, YING, et al.
Publicado: (2014)

Lack of Acid Sphingomyelinase Induces Age-Related Retinal Degeneration
por: Wu, Bill X., et al.
Publicado: (2015)

Structure of the cystathionine γ-synthase MetB from Mycobacterium ulcerans
por: Clifton, Matthew C., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_9hncjd57ilvgq520je287vmke8