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Acid Sphingomyelinase Gene Knockout Ameliorates Hyperhomocysteinemic Glomerular Injury in Mice Lacking Cystathionine-β-Synthase

Acid sphingomyelinase (ASM) has been implicated in the development of hyperhomocysteinemia (hHcys)-induced glomerular oxidative stress and injury. However, it remains unknown whether genetically engineering of ASM gene produces beneficial or detrimental action on hHcys-induced glomerular injury. The...

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Detalles Bibliográficos
Autores principales:	Boini, Krishna M., Xia, Min, Abais, Justine M., Xu, Ming, Li, Cai-xia, Li, Pin-Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443210/ https://www.ncbi.nlm.nih.gov/pubmed/23024785 http://dx.doi.org/10.1371/journal.pone.0045020

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