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Evaluation of a Novel Assay for Detection of the Fetal Marker RASSF1A: Facilitating Improved Diagnostic Reliability of Noninvasive Prenatal Diagnosis

BACKGROUND: Analysis of cell free fetal (cff) DNA in maternal plasma is used routinely for non invasive prenatal diagnosis (NIPD) of fetal sex determination, fetal rhesus D status and some single gene disorders. True positive results rely on detection of the fetal target being analysed. No amplifica...

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Detalles Bibliográficos
Autores principales: White, Helen E., Dent, Carolyn L., Hall, Victoria J., Crolla, John A., Chitty, Lyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443218/
https://www.ncbi.nlm.nih.gov/pubmed/23024794
http://dx.doi.org/10.1371/journal.pone.0045073